Neuromyogenic properties of the internal anal sphincter: therapeutic rationale for anal fissures
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چکیده
منابع مشابه
Neuromyogenic properties of the internal anal sphincter: therapeutic rationale for anal fissures.
Lateral sphincterotomy diminishes internal anal sphincter hypertonia and thereby reduces anal canal pressure. This improves anal mucosal blood flow and promotes the healing of anal fissures. However, sphincterotomy can be associated with long term disturbances of sphincter function. The optimal treatment for an anal fissure is to induce a temporary reduction of anal canal resting pressure to al...
متن کاملNeuromyogenic Properties of the Internal Anal Sphincter: Applications for the Treatment of Anal Fissures
Pharmacological therapy of anal fissures reduces maximum resting pressure (MRP), allowing healing by promoting anodermal vascular perfusion. In this thesis the clinical and manometric responses to diltiazem and botulinum toxin and the therapeutic potential of indoramin and salbutamol were investigated. A porcine internal anal sphincter model was developed to validate the responses to pharmacolo...
متن کاملInternal anal sphincter: Clinical perspective.
OBJECTIVE To summarise current knowledge of Internal anal sphincter. BACKGROUND The internal anal sphincter (IAS) is the involuntary ring of smooth muscle in the anal canal and is the major contributor to the resting pressure in the anus. Structural injury or functional weakness of the muscle results in passive incontinence of faeces and flatus. With advent of new assessment and treatment mod...
متن کاملPhysio-pathology of the internal anal sphincter.
In normal physiological studies, using electrical, manometric, or cinematographic methods, it is practically impossible to separate the role of the internal sphincter from that of the other elements of the functional ensemble forming the anal sphincteric system (Aron and Thouvenot, 1962; Lawson and Nixon, 1967; Schnaufer et al., 1967). It is only by studying the pathology of the area that it is...
متن کاملInternal anal sphincter evaluation using 3D anal ultrasound.
A 42 year-old male, with no relevant medical history except surgery three years before for chronic anal fissure in another center (without information regarding type of surgery), attended outpatient clinic for several week-history of anal pain. The patient related a sudden anal pain without irradiation and without relationship with defecation that improved with flexion of the lower extremities....
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ژورنال
عنوان ژورنال: Gut
سال: 2000
ISSN: 0017-5749
DOI: 10.1136/gut.46.6.861